Search results for " regeneration"
showing 10 items of 619 documents
Persistent inflammation alters the function of the endogenous brain stem cell compartment
2008
Endogenous neural stem/precursor cells (NPCs) are considered a functional reservoir for promoting tissue homeostasis and repair after injury, therefore regenerative strategies that mobilize these cells have recently been proposed. Despite evidence of increased neurogenesis upon acute inflammatory insults (e.g. ischaemic stroke), the plasticity of the endogenous brain stem cell compartment in chronic CNS inflammatory disorders remains poorly characterized. Here we show that persistent brain inflammation, induced by immune cells targeting myelin, extensively alters the proliferative and migratory properties of subventricular zone (SVZ)-resident NPCs in vivo leading to significant accumulation…
Role of caspase-8 in hepatocyte response to infection and injury in mice.
2007
Caspase-8 has been implicated in signaling for apoptotic cell death and for certain nonapoptotic functions. However, knowledge of actual physiological or pathophysiological processes to which this enzyme contributes is lacking. Using a mouse model and employing the conditional knockout approach to delete the caspase-8 gene specifically in the liver, we found that caspase-8 deficiency in hepatocytes facilitates infection of the liver by Listeria monocytogenes, attenuates the hepatocyte proliferation wave during the first 48 hours after partial hepatectomy and, depending on the genetic background of the mice, prompts a chronic inflammatory response to the hepatectomy, as a result of which the…
New exclusion limits on scalar and pseudoscalar axionlike particles from light shining through a wall
2015
Physics beyond the Standard Model predicts the possible existence of new particles that can be searched at the low-energy frontier in the sub-eV range. The OSQAR photon regeneration experiment looks for ``light shining through a wall'' from the quantum oscillation of optical photons into ``weakly interacting sub-eV particles,'' such as axion or axionlike particles (ALPs) in a 9 T transverse magnetic field over a length of $2\ifmmode\times\else\texttimes\fi{}14.3\text{ }\text{ }\mathrm{m}$. In 2014, this experiment was run with an outstanding sensitivity, using an 18.5 W continuous wave laser emitting in the green at the single wavelength of 532 nm. No regenerated photons have been detected …
(Good Practice) Paris, Promenade Plantée. Recycling a landscape infrastructure
2014
The contribute describes the case of study of Promenade Plantée in Paris and the project of transformation of a dismissed urban infrastructure in a landscape resource.
Collective participation for the sustainable redevelopment of degraded environments and urban public space
2022
The use of participatory processes as useful tools for the regeneration of the built environment is urgently topical, also in view of the inclusive forms of decision-making that have been introduced for years by ministerial and European standards. The research is part of a well-structured cultural and regulatory context characterised by new and interesting experiments in the field. Studying the participatory process as a useful strategy for conflict management and for the construction of new regenerative models in fact also implies a clarification of "what is meant by participation and the participatory project. At the same time, as widely testified to by the production of manuals in recent…
Numerical study of an optical regenerator exploiting self-phase modulation and spectral offset filtering at 40 Gbit/s
2008
Topic: Nonlinear optics; International audience; In this work, we numerically investigate the performances of optical regenerators based on self-phase modulation and spectral offset filtering at 40 Gbit/s. We outline the different effects affecting the device performances and explain the choice of the optimal working power. The impact of the regenerator on the output signal is also analysed through a statistical approach. Both single- and double-stage configurations are investigated.
Clinical parameters of implants placed in healed sites using flapped and flapless techniques: A systematic review
2017
Background: Dental implant placement using flapless surgery is a minimally invasive technique that improves blood supply compared with flapped surgery. However, the flapless technique does not provide access to allow bone regeneration. Objectives: The aim of this systematic review was to evaluate the clinical parameters following implant surgery in healed sites, using two procedures: flapped vs. flapless surgery. Material and Methods: A detailed electronic search was carried out in the PubMed/Medline, Embase and Cochrane Library databases. The focused question was, “How do flapped and flapless surgical techniques affect the clinical parameters of dental implants placed in healed sites?”. Al…
La rigenerazione urbana delle periferie degradate: il caso emblematico della città di Palermo
2020
Il saggio esamina le nuove tendenze della legislazione in materia di rigenerazione urbanistica, con particolare attenzione alla vicenda urbanistica del Comune di Palermo.
URBAN REGENERATION PROCESSES IN RIGA
2013
ANOTĀCIJA Pilsētas revitalizācijas process ir nozīmīga tēma mūsdienu pilsētu ģeogrāfijas pētījumos, un to raksturo dažādas formas un izpausmes. Rīgā kopš Latvijas valstiskās neatkarības atjaunošanas ir notikuši dažādi pilsētu pārmaiņu procesi. Svarīga loma šajos pilsētas pārmaiņu procesos ir pilsētas revitalizācijas procesiem, kuru rezultātā tiek revitalizētas un atkārtoti izmantotas degradētas teritorijas, tādējādi veicinot ilgtspējīgu pilsētas attīstību. Promocijas darba „Pilsētas revitalizācijas procesi Rīgā” mērķis ir izvērtēt pilsētas attīstības procesus, analizējot pilsētas revitalizācijas izpausmes Rīgā. Pētījuma ietvaros tika izstrādāta atbilstoša metodika pilsētas revitalizācijas p…
Biostable Scaffolds of Polyacrylate Polymers Implanted in the Articular Cartilage Induce Hyaline-Like Cartilage Regeneration in Rabbits
2017
[EN] Purpose: To study the influence of scaffold properties on the organization of ¿in vivo¿ cartilage regeneration. Our hypothesis is that stress transmission to the cells seeded inside the scaffold pores or surrounding it, which is highly dependent on the scaffold properties, determine differentiation of both mesenchymal cells and dedifferentiated autologous chondrocytes. Methods: Four series of porous scaffolds made of different polyacrylate polymers, previously seeded with cultured rabbit chondrocytes or without cells preseeded, were implanted in cartilage defects in rabbits. Subchondral bone was always injured during the surgery in order to allow blood to reach the implantation site an…